Use champion's 1st ability. For abilities that target a champion, you must follow this by either left-clicking the champion or pressing F1 - F5 to target a team member. Same for W, E, and R keys

Use champion's 2nd ability

Use champion's 3rd ability

Use champion's 4th ability (Ultimate)

Add an ability point to the champion's 1st ability

Smart cast champion's 1st ability

Smart cast champion's 2nd ability

Attack Move (Champion moves to point, stopping to attack any enemies along the way)

Stop Command (Champion stops their current course of action)

Use trinket

Recall

Open champion statistics page

Toggle alert ping cursor

Toggle camera lock on champion

Center camera on champion (holding Space will hold the camera on the champion until released)

Toggle retreat ping cursor. Clicking with this hotkey on an allied champion (or their icon in the upper left area of the screen) will show an alert telling that specific champion to fall back

Ping location/Open Radial Menu

Retreat Ping location/Open Radial Menu

Move camera to corresponding ally champion (camera must be unlocked)

Open chat with "/all" already written