Microsoft Publisher 2021 keyboard shortcuts ‒ DefKey

These shortcuts are using the ribbon, that's the reason they're key sequences rather than usual "hold and press" hotkeys. To use these shortcuts, just tap the keys in given order, without holding them.
0	Alt then J then D then S then E	Open Shape Effects menu
0	Alt then J then D then S then E then S	(then Tab through options) Open the Shape Effects - Shadow Gallery
0	Alt then J then D then S then E then R	(then Tab through options) Open the Shape Effects - Reflection Gallery
0	Alt then J then D then S then E then G	(then Tab through options) Open the Shape Effects - Glow Gallery
0	Alt then J then D then S then E then E	(then Tab through options) Open the Shape Effects - Soft Edges Gallery
0	Alt then J then D then S then E then B	(then Tab through options) Open the Shape Effects - Bewel Gallery
0	Alt then J then D then S then E then D	(then Tab through options) Open the Shape Effects - 3-D Rotation Gallery
0	Alt then J then D then S then T	(then Tab through options) Open the Shape Styles Gallery

0	Alt then J then P then P then E	Open the Picture effects menu
0	Alt then J then P then P then E then S	(then tab through options) Open the Picture effects - Shadow Gallery
0	Alt then J then P then P then E then R	(then tab through options) Open the Picture effects - Reflection Gallery
0	Alt then J then P then P then E then G	(then tab through options) Open the Picture effects - Glow Gallery
0	Alt then J then P then P then E then E	(then tab through options) Open the Picture effects - Soft Edges Gallery
0	Alt then J then P then P then E then B	(then tab through options) Open the Picture effects - Bevel Gallery
0	Alt then J then P then P then E then D	(then tab through options) Open the Picture effects - 3-D Rotation Gallery
0	Alt then J then P then K	(then tab through options) Open the Picture Styles Gallery
1	Alt then J then P then K then C	Clear Picture Style

0	Alt then J then X then T then I	Open Text Fill Dropdown
0	Alt then J then X then T then I then N	No Fill
0	Alt then J then X then T then I then M	More Fill Colors…
0	Alt then J then X then T then I then F	Fill Effects…
0	Alt then J then X then T then I then T	Tints
0	Alt then J then X then T then I then S	Sample Font Color

0	Alt then J then X then T then O	Open Text Outline Dropdown
0	Alt then J then X then T then O then N	No Outline
0	Alt then J then X then T then O then M	More Outline Colors…
0	Alt then J then X then T then O then O	Outline Effects…
0	Alt then J then X then T then O then S	Sample Line Color
0	Alt then J then X then T then O then W	Weight
0	Alt then J then X then T then O then D	Dashes

0	Alt then J then X then T then E	Open Text Effects Dropdown
0	Alt then J then X then T then E then S	Shadow
0	Alt then J then X then T then E then R	Reflection
0	Alt then J then X then T then E then G	Glow
0	Alt then J then X then T then E then B	Bevel

All shortcuts below are usual hotkeys (contrary to Ribbon shortcuts above), meaning you'll need to hold Ctrl, Shift or Alt modifier key if that shortcut includes those.
0	Ctrl + N	Open a new instance of Publisher
0	Ctrl + O	Display the Open Publication dialog box
0	Ctrl + F4	Close the current publication
0	or Ctrl + W
0	Ctrl + S	Display the Save As dialog box

0	F3	Display the Find and Replace task pane, with the Find option selected
0	or Ctrl + F
0	or ↑ Shift + F4
0	Ctrl + H	Display the Find and Replace task pane, with the Replace option selected
0	F7	Check spelling
0	↑ Shift + F7	Display the Thesaurus task pane
0	Alt +	(click a word) Display the Research task pane
0	Ctrl + A	Select all the text (If the cursor is in a text box, this selects all text in the current story; if the cursor is not in a text box, this selects all the objects on a page.)
0	Ctrl + B	Make text bold
0	Ctrl + I	Italicize text
0	Ctrl + U	Underline text
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0	Ctrl + ↑ Shift + K	Make text small capital letters, or return small capital letters to upper and lower case
0	Ctrl + ↑ Shift + F	Open the Font dialog
0	Ctrl + ↑ Shift + C	Copy formatting
0	Ctrl + ↑ Shift + V	Paste formatting
0	Ctrl + ↑ Shift + Y	Turn Special Characters on or off
0	Ctrl + Space	Return character formatting to the current text style
0	Ctrl + =	Apply or remove subscript formatting
0	Ctrl + ↑ Shift + =	Apply or remove superscript formatting
0	Ctrl + ↑ Shift + ]	Increase space between letters in a word (kerning)
0	Ctrl + ↑ Shift + [	Decrease space between letters in a word (kerning)
0	Ctrl + ]	Increase font size by 1.0 point
0	Ctrl + [	Decrease font size by 1.0 point
0	Ctrl + ↑ Shift + >	Increase to the next size in the Font Size box
0	Ctrl + ↑ Shift + <	Decrease to the next size in the Font Size box
0	Ctrl + E	Center a paragraph
0	Ctrl + L	Align a paragraph on the left
0	Ctrl + R	Align a paragraph on the right
0	Ctrl + J	Align a paragraph on both sides (justified)
0	Ctrl + ↑ Shift + D	Distribute a paragraph evenly horizontally
0	Ctrl + ↑ Shift + J	Set newspaper alignment for a paragraph (East Asian languages only)
0	Ctrl + ↑ Shift + H	Display the Hyphenation dialog box
0	Alt + ↑ Shift + T	Insert the current time
0	Alt + ↑ Shift + D	Insert the current date
0	Alt + ↑ Shift + P	Insert the current page number
0	Ctrl + ↑ Shift + 0	Prevent the word from getting hyphenated if it occurs at the end of a line

0	Ctrl + ↑ Shift + C	Copy formatting from the selected text
0	Ctrl + ↑ Shift + V	Apply copied formatting to text

0	Ctrl + C	Copy the selected text or object
0	or Ctrl + Insert
0	Ctrl + X	Cut the selected text or object
0	or ↑ Shift + Del
0	Ctrl + V	Paste text or an object
0	or ↑ Shift + Insert
0	Del	Delete the selected object
0	or Ctrl + ↑ Shift + X

0	Ctrl + Z	Undo what you last did
0	or Alt + Backspace
0	Ctrl + Y	Redo what you last did
0	or F4

0	← ↑ → ← ↓ →	Nudge a selected object up, down, left, or right
0	Alt + ← ↑ → ← ↓ →	If the selected object has a cursor in its text, nudge the selected object up, down, left, or right

0	Alt + F6	Bring object to front
0	Alt + ↑ Shift + F6	Send object to back

0	F10	Turn Snap to Guides on or off
0	or ↑ Shift + R
0	or ↑ Shift + S
0	or ↑ Shift + M

0	Ctrl + A	Select all objects on the page (If your cursor is in a text box, this selects all the text in a story)
0	Ctrl + ↑ Shift + G	Group selected objects, or ungroup grouped objects
0	Esc	Clear the selection from selected text
0	Esc	Clear the selection from a selected object
0	Esc	Select the object within the group — if that object contains selected text

0	F5	Display the Go To Page dialog box
0	or Ctrl + G
0	Ctrl + ↑ Shift + N	Insert a page or a two-page spread. If you are creating a newsletter, it opens the Insert publication type Pages dialog box
0	Ctrl + ↑ Shift + U	Insert duplicate page after the selected page

0	F5	Display the Go To Page dialog box.
0	or Ctrl + G
0	Ctrl + Page Down	Go to the next page
0	Ctrl + Page Up	Go to the previous page
0	Ctrl + M	Switch between the current page and the master page

or Ctrl + M

0	Ctrl + ↑ Shift + O	Turn Boundaries on or off
0	Ctrl + F7	Turn Horizontal Baseline Guides on or off (not available in web view)
0	Ctrl + ↑ Shift + F7	Turn Vertical Baseline Guides on or off (East Asian languages only—not available in web view)

0	F9	Switch between the current view and the actual size
0	Ctrl + ↑ Shift + L	Zoom to full page view

These keyboard shortcuts are available when you're in Print view and affect the print preview pane.
0	F9	Switch between the current view and the actual size
0	↑ ↓	Scroll up or down
0	← →	Scroll left or right
0	Page Up	Scroll up in large increments
0	or Ctrl + ↑
0	Page Down	Scroll down in large increments
0	or Ctrl + ↓
0	Ctrl + ←	Scroll left in large increments
0	Ctrl + →	Scroll right in large increments

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